Research on the New Chlorination Process of the Key Intermediate of Oxacephem Mother Nucleus
A new process for the chlorination of the key intermediate of oxacephem mother nucleus was studied in this paper.In this process,t-BuOCl/HCl was used as the chlorination system,and the yield was above 83%.This method has the advantages of better safety,higher yield and more environmental friendliness compared with the traditional chlorine chlorination.