Mathematical Research and Application Progress of Chemodynamic Therapy for Selective Tumor Treatment Model
Chemodynamic therapy has attracted much attention due to its unique reactive oxygen species production mode,which has become an emerging cancer treatment modality.Nanomedicine was designed to deliver Fenton reagent to the tumor site,and based on the Fenton reaction,H2O2 expressed in the tumor microenvironment was converted into oxidative·OH,which induces oxidative damage in cancer cells.The efficiency of the Fenton response directly affects the treatment effect,and more and more studies have shown that the current efficacy is far from enough to completely cure the tumor.In this review,we review the main heterogeneous catalysts used in this technology,the main reaction pathways and their mechanisms,including how to propose mechanistic strategies to enhance the Fenton reaction.This review provides a reference for the study of Fenton reaction and puts forward some suggestions for the development direction of future research.
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维普
