Ginkgo biloba is widely used in the prevention and treatment of various diseases due to its rich medicinal ingredients.The main effective ingredients are flavonoids,tannins,and polysaccharides.Wait for a variety of pharmacological activity.In recent years,the optimization of the effective ingredient extraction process of ginkgo leaves has become a hotspot of scientific research.Traditional water lifting and alcoholism are simple and low in cost,but there are insufficient in terms of extraction efficiency and the purity of the composition.Modern ultrasound,microwave,and supercritical fluid extraction technology significantly improved the extraction efficiency,and showed advantages in maintaining composition activity.This review aims to systematically discuss the development of the effective ingredient extraction process of Ginkgo biloba leaves and the application status of modern extraction technology at home and abroad,and provide reference and guidance for the in-depth development and application of ginkgo leaves.