A comparative study of heart rate variability in patients with bipolar disorder and generalized anxiety disorder
Objective To explore the differences in heart rate variability(HRV)between patients with bipolar disorder(BD)and generalized anxiety disorder(GAD).Methods A total of 57 patients with BD(BD group)and 60 patients with GAD(GAD group)were selected and tested for HRV,and their HRV-related indicators SDNN-24(24 h-standard diviation of NN intervals),SDNN(standard deviation of NN intervals),SDANN(standard deviation of average NN intervals in all 5 min segments of the entire recording),rMSSD(root mean square difference between adjacent R-R intervals),PNN50(percentage of difference between adjacent R-R intervals>50 ms),TP(total power),LF(low-frequency power),HF(high-frequency power),and the ratio between LF and HF(LF/HF)were compared.Results The disease course of GAD group was shorter than that of BD group(P<0.01).The indicators of SDNN-24 and SDANN in GAD group were lower than those in BD group(P<0.01).Correlation analysis showed that the disease course was negatively correlated with TP,LF,HF and SDNN in GAD group(P<0.05).Conclusion The somatoform autonomic dysfunction of GAD patients is more serious than that of BD patients.The disease course of GAD patients can affect their HRV indicators.
万方数据
维普
