The effect of whole course management combined with group cognitive behavioral therapy in the treatment of first-episode depression
Objective To explore the effects of whole course management combined with group cognitive behavioral therapy on depression,anxiety,and quality of life in patients with first-episode depression.Methods A total of 75 patients with first-episode depression were selected and divided into study group(n=40)treated with routine medication and whole course management combined with group cognitive behavioral therapy and control group(n=35)treated only with routine medication.At baseline and at the ends of 8th,16th and 24th weeks after treatment,they were all assessed with Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA)and Quality of Life Enjoyment and Satisfaction Questionnaire Short Form(Q-LES-Q-SF).The scores of HAMD,HAMA,and Q-LES-Q-SF between two groups were compared using repeated measures analysis of variance.Results Repeated measures analysis of variance showed that there existed significant differences in interaction effects of time and group for scores of HAMD,HAMA,and Q-LES-Q-SF(P＜0.001).At the ends of 8th,16th and 24th weeks after treatment,the scores of HAMD and HAMA in both groups decreased significantly compared with those at the baseline(P＜0.05),and the scores of HAMD and HAMA in study group were lower than those in control group(P＜0.001).In study group,the Q-LES-Q-SF scores at the 8th,16th and 24th weeks after treatment increased compared with that at baseline,and were higher than those in control group(P＜0.05).In control group,the Q-LES-Q-SF scores at the 8th and 24th weekends after treatment increased compared with that at baseline(P＜0.05).Conclusion Whole course management combined with group cognitive behavioral therapy can improve depression,anxiety,and quality of life in patients with depression,with good long-term efficacy.
Whole course management modeGroup cognitive behavioral therapyDepressionQuality of lifeAnxiety
万方数据
维普
