In the current context of actively promoting production-education integration,universities should explore how to cultivate engineering and technical talents with engineering practical and innovative abilities.Graduation project is an important teaching link to cultivate students'engineering practical abilities and showcase their comprehensive qualities.This paper takes the Mechanical Engineering major of our school as an example,analyzing the characteristics of the Mechanical Engineering and its requirements for graduation projects,moreover,discusses the advantages of school-enterprise cooperation in guiding graduation projects,the construction of models,and the content of implementation and organizational management.This paper is designed to offer a new perspective and practical guidance for the education of Mechanical Engineering,and its purpose is to cultivate more high-quality engineering and technical talents who can meet the needs of social development.