Heme iron combined with hemoglobin or myoglobin can be absorbed by intestinal epithelial cells directly in the form of ferroporphyrin. It is an ideal ecological iron agent that will not cause adverse reaction and phytic acid ion does not affect the absorption of hemoglobin, so it is widely used in food and health care products. In addition, heme iron is also used as an anti-cancer drug or functional material in medicine, chemical industry and so on. This paper will introduce the preparation, function and application of heme iron.