Objective To establish a method for the detection of perilla leaf volatile oil adulterated with cinnamon bark oil in Tongxuanlifei Granules.Methods The volatile components were enriched by collecting the volatile oil of Tongxuanlifei Granules,and cinnamaldehyde in Tongxuanlifei Granules was determined by HPLC.Octadecylsilane bonded silica gel was used as filler.The mobile phase was acetonitrile-water(35∶65).The detection wavelength was 290 nm;The column temperature was 35℃;The flow rate was 1.0 ml/min;The injection volume was 10 μl.Results Cinnamaldehyde was detected in 42 batches(41 production batch numbers,2 production enterprises)out of 97 batches(83 production batch numbers,10 production enterprises)of Tongxuanlifei Granules.Conclusion The method can identify the adulterated cinnamaldehyde in Tongxuanlifei Granules.It has strong specificity and good reproducibility,which plays a certain role in supervision of the quality of the Chinese patent medicine.
维普
万方数据