Study on Applicability of Method for Examination of Children's Cosmetics and Inspection of Controlled Bacteria
Objective To investigate the hygienic quality of children's cosmetics and to study the applicability of the method for controlled bacteria.Methods According to Technical Specification for Cosmetic Safety(2015 edition),83 batches of commonly sold children's cosmetics were examined for microorganisms,and the applicability test of method for controlled bacteria in children's cosmetics was conducted by referring to Chinese Pharmacopoeia(2020 edition).At the same time,according to the classification of different dosage forms,the addition of different preservatives in each dosage form and the types of the preservatives added to the antibacterial samples were analyzed.Results The qualified rate of 83 batches of children's cosmetics by microbial inspection was 100％,indicating that the hygienic quality of children's cosmetics on the market was very good according to the current standard,but the applicability test of the controlled bacteria inspection method showed that 12 batches of 83 batches of samples had different degrees of bacteriological inhibition,and the bacteriological inhibition rate was 14.5％.Some samples needed to be diluted by medium or film filtration combined with the addition of neutralizing agents to eliminate the antibacterial activity,so as to pass the applicability test,indicating that some children's cosmetics had strong antibacterial activity.The statistical results of preservatives showed that the use rate of phenoxyethanol was the highest in children's cosmetics,followed by sodium benzoate and methyl hydroxybenzoate,and children's cosmetics with different dosage forms had relatively exclusive applicability to the types of preservatives added.The statistical situation of antibacterial ingredients showed that chlorophenyl ether and benzoic acid had stronger antibacterial properties.Conclusion It is recommended to carry out method applicability test before controlled bacteria inspection of children's cosmetics,and select some safe and effective preservatives with weak antibacterial properties in the selection of children's preservatives,which can provide some references for children's cosmetics manufacturers.
万方数据
维普
