Human Feeding Trial of Ginkgo Folium Capsules for Evaluation of Auxiliary Lipid-lowering Function
Objective To observe the safety and effectiveness of Ginkgo Folium Capsules at the recommended dose in human feeding trial for evaluation of auxiliary lipid-lowering function.Methods 110 patients with hyperlipidemia who met the test criteria were selected and randomly divided into trial group(55 cases)and control group(55 cases).The patients in trial group took one capsule twice daily,while the patients in control group took placebo.Results Before and after the trial,the average values of various safety indexes,such as blood pressure,hemogram,heart rate,excrement,blood sugar concentration,liver and kidney function,were all within the normal range,and no allergy or adverse reactions occurred during the trial.After administration of Ginkgo Folium Capsules for 60 days,the serum high density lipoprotein cholesterol(HDL-C)level of the trial group was lower than that of the control group,and the difference was not statistically significant(P>0.05).The levels of low-density lipoprotein cholesterol(LDL-C),triglyceride(TG)and serum total cholesterol(TC)decreased significantly,and the differences between the levels of the indexes before after the trial and the differences between the levels of the indexes of the trial group and the control group were all statistically significant(P<0.05).After the trial,the total effective rate of clinical observation of the trial group(84.9%)was significantly higher than that of the control group(44.2%),and the difference was statistically significant(P<0.05).Conclusion Ginkgo Folium Capsules show no obvious harm to the health of the subjects,and has auxiliary lipid-lowering effect at the experimental dose.
Ginkgo Folium Capsuleshuman feeding trialsafetylipid-lowering function
万方数据
维普
