Objective To establish an ion chromatography method for the determination of hydrogen cyanide in Xingsu Zhike Syrup.Methods Ion chromatography was performed on Thermo Fisher Dionex Ion Pac AS11 analytical column(4 mm×250 mm)and Thermo Fisher Dionex Ion Pac AG11 guard column(4 mm×50 mm)at the temperature of 35℃,using 0.05 mol/L NaOH solution at a flow rate of 0.8 ml/min as mobile phase.Meanwhile,a pulsed ampere detector was used for detection,a silver electrode was used as the working electrode,and an Ag/AgCl electrode was used as the reference electrode.A triple-potential system was used for potential detection,and the injection volume was set as 25 μl.Results There was a good linear relationship in the range of 0.05-25.00 μg/ml for hydrocyanic acid,with R2 of 0.9990.The average recovery was 100.32%.Conclusion This method is simple,rapid,specific,sensitive,reproducible and reliable,and can be used for the large-scale and rapid determination of Xingsu Zhike Syrup.
关键词
离子色谱法/杏苏止咳糖浆/氢氰酸
Key words
ion chromatography/Xingsu Zhike Syrup/hydrogen cyanide
维普
万方数据