食品与药品2024,Vol.26Issue(3) :256-260.DOI:10.3969/j.issn.1672-979X.2024.03.013

2种自拟胶囊改善黄褐斑的人体试食研究

Human Experimental Study on Improvement of Melasma by Two Kinds of Self-designed Capsules

李文静 杨健峰 王梓懿 何蕊 李信心 于洋 苏学峰
食品与药品2024,Vol.26Issue(3) :256-260.DOI:10.3969/j.issn.1672-979X.2024.03.013

2种自拟胶囊改善黄褐斑的人体试食研究

Human Experimental Study on Improvement of Melasma by Two Kinds of Self-designed Capsules

李文静 1杨健峰 1王梓懿 1何蕊 1李信心 1于洋 1苏学峰2
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作者信息

  • 1. 西北大学 化工学院,陕西省可降解生物医用材料重点实验室,陕西省生物材料与发酵工程技术研究中心,陕西 西安 710069
  • 2. 西安市中心医院,陕西 西安 710004
  • 折叠

摘要

目的 观察2种自拟胶囊改善黄褐斑的作用.方法 将162例黄褐斑患者随机分为对照组(n=54)、研究组1(n=54,后期2例脱失筛除)和研究组2(n=54),脱失率1.23%.对照组以维生素C和维生素E联合予以治疗;研究组1以自拟组方1(桃仁、茯苓、当归)予以治疗;研究组2以自拟组方2(红花、桃仁、茯苓、当归)予以治疗.结果 对照组、研究组1和研究组2的改善黄褐斑的有效率依次为35.19%、55.77%和66.67%,两个研究组的有效率与对照组比较均具有统计学意义(P<0.05,P<0.01),且研究组2的效果更好.结论 两种自拟胶囊均有助于改善黄褐斑.

Abstract

Objective To observe the effect of two self-designed capsules on improving melasma.Methods One hundred and sixty-two patients with melasma were randomly divided into control group(n=54),study group 1(n=54,with 2 cases of late loss of screening)and study group 2(n=54),with a loss rate of 1.23%.The control group was treated with vitamin C and vitamin E.Study group 1 was treated with self-made formula 1(Persicae Semen,Poria and Angelicae Sinensis Radix).Study group 2 was treated with self-made formula 2(Carthami Flos,Semen Persicae,Poria and Angelicae Sinensis Radix).Results The improvement rates of the control group,study group 1 and study group 2 were 35.19%,55.77%and 66.67%,respectively.The improvement rates of the two study groups were statistically significant compared with the control group(P<0.05,P<0.01).The improvement effect of study group 2 was better,indicating that Carthami Flos had the effect of removing melasma.Conclusion Both self-designed capsules helps to improve melasma.

关键词

红花/桃仁/当归/茯苓/黄褐斑

Key words

Carthami Flos/Persicae Semen/Angelicae Sinensis Radix/Poria/melasma

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出版年

2024
食品与药品
山东省生物药物研究院

食品与药品

CSTPCD
影响因子:0.537
ISSN:1672-979X
参考文献量11
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