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系统性红斑狼疮治疗药物研究进展

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系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种由致病性自身抗体和免疫复合物介导器官、组织损伤的自身免疫病.其治疗药物主要包括抗炎药、靶向治疗药物、免疫治疗药物和中药等.SLE的发生和发展是复杂的病理生理过程,其中每一过程均有潜在的可干预途径,随着对SLE机制研究的不断深入,治疗药物也不断涌现.本文综合国内外文献,对目前几类主要的SLE药物研究进展进行综述,旨在为SLE的治疗提供参考.
Research Progress on Therapeutic Drugs for Systemic Lupus Erythematosus
Systemic lupus erythematosus(SLE)is an autoimmune disease with organ and tissue damage mediated by pathogenic autoantibodies and immune complexes.Its therapeutic drugs mainly include anti-inflammatory drugs,targeted therapeutic drugs,immunotherapy drugs and traditional Chinese medicine.The occurrence and development of SLE are complex pathophysiological processes,each of which has potential intervention pathways.With the deepening of the study on the mechanism of SLE,therapeutic drugs are constantly emerging.Based on domestic and foreign literatures,research progress on several main drugs for SLE is reviewed in this paper,aiming at providing reference for the treatment of SLE.

systemic lupus erythematosusanti-inflammatory drugimmunotherapytraditional Chinese medicine

李德鑫、程振田、马玉奎

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齐鲁师范学院 化学与化工学院,山东 济南 250200

潍坊市益都中心医院,山东 潍坊 262500

系统性红斑狼疮 抗炎药 免疫治疗 中药

2024

食品与药品
山东省生物药物研究院

食品与药品

CSTPCD
影响因子:0.537
ISSN:1672-979X
年,卷(期):2024.26(4)
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