系统性红斑狼疮治疗药物研究进展
Research Progress on Therapeutic Drugs for Systemic Lupus Erythematosus
李德鑫 1程振田 2马玉奎1
作者信息
- 1. 齐鲁师范学院 化学与化工学院,山东 济南 250200
- 2. 潍坊市益都中心医院,山东 潍坊 262500
- 折叠
摘要
系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种由致病性自身抗体和免疫复合物介导器官、组织损伤的自身免疫病.其治疗药物主要包括抗炎药、靶向治疗药物、免疫治疗药物和中药等.SLE的发生和发展是复杂的病理生理过程,其中每一过程均有潜在的可干预途径,随着对SLE机制研究的不断深入,治疗药物也不断涌现.本文综合国内外文献,对目前几类主要的SLE药物研究进展进行综述,旨在为SLE的治疗提供参考.
Abstract
Systemic lupus erythematosus(SLE)is an autoimmune disease with organ and tissue damage mediated by pathogenic autoantibodies and immune complexes.Its therapeutic drugs mainly include anti-inflammatory drugs,targeted therapeutic drugs,immunotherapy drugs and traditional Chinese medicine.The occurrence and development of SLE are complex pathophysiological processes,each of which has potential intervention pathways.With the deepening of the study on the mechanism of SLE,therapeutic drugs are constantly emerging.Based on domestic and foreign literatures,research progress on several main drugs for SLE is reviewed in this paper,aiming at providing reference for the treatment of SLE.
关键词
系统性红斑狼疮/抗炎药/免疫治疗/中药Key words
systemic lupus erythematosus/anti-inflammatory drug/immunotherapy/traditional Chinese medicine引用本文复制引用
出版年
2024
NETL
NSTL
万方数据