Objective To investigate the clinical characteristics of vaccine-associated uveitis in order to provide a reference for vac-cine safety monitoring,vaccination,and clinical diagnosis and treatment.Methods The vaccine-associated uveitis reports from 1990 to 2022 were collected from the American Vaccine Adverse Event Reporting System.Moreover,sex,age,type of vaccination,dose series,time of occurrence,and type of uveitis of vaccine-associated uveitis reports were retrospectively analyzed.Results Of the 317 cases of vaccine-associated uveitis,more than 10 types of vaccine were involved,mainly the COVID-19 vaccine,human papillomavirus vaccine,and hepatitis B vaccine.There were 86 males and 231 females,with a male-to-female ratio of 1:2.7.Patients aged 18-＜60 years,accounted for the majority of the total cases(65.3%).Uveitis is common under 8 days after vaccina-tion and after the first dose of vaccination,accounting for 56.8%and 47.0%,respectively.Iridocyclitis represented the highest pro-portion of 184(56.5%)cases of uveitis.Conclusion Fully understand and study this adverse reaction to vaccination in depth,con-tinue to monitor vaccine safety,better vaccination,and clinical diagnosis and treatment.
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