Objective This report describes the pathogenesis in a patient with no history of vegetative trauma who was diagnosed with fungal endophthalmitis combined with diabetes mellitus.Methods A 53-year-old male patient with sharply decreased visual acuity in the left eye did not significantly improve after receiving glucocorticoid treatment for shock in an outside hospital.Fifteen d later,intraocular fluids analysis was performed in the Ophthalmology Department of Qilu Hospital of Shandong University to identify the causative organism.Moreover,ultrasonic emulsification for cataract,vitrectomy,intraocular laser,silicone oil filling,and intravitreal injection(voriconazole,0.02 mg)were performed in the left eye.Results Postoperative vitreous fluid was submitted for staining:fungus(-).Corrected visual acuity:0.1 in the right eye and HM/5cm in the left eye and stable condition of the poste-rior anterior segment of the eye were found.Conclusion Fusarium is a rare but recognized cause of endogenous endophthalmitis in immunocompromised patients via various routes of infection.Diabetes mellitus and steroid hormone application could reduce the sta-bility of the patient's immune system.Timely diagnosis and antifungal treatment were very important for improving the patient's prognosis.
Endogenous endophthalmitisHistory of vegetative traumaDiabetes mellitusFusariumGlucocorticoids
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