Objective To explore the short-term clinical effect of drug sustained-release stent implantation in functional endoscopic sinus surgery for refractory sinusitis.Methods Sixty patients with refractory sinusitis were randomized observation group and con-trol group.Both groups of patients underwent functional endoscopic sinus surgery.The observation group received sinus drug sus-tained-release stent during surgery,while the control group received routine medication after surgery.Four weeks after surgery,all patients underwent the sino-nasal outcome test-20(SNOT-20)for subjective symptom scoring,and nasal endoscopy and CT scan were performed for objective evaluation of mucosal recovery based on the Lund-Kennedy and CT Lund-Mackay scores of the sinu-ses.The clinical efficacy,incidence of complications,and recurrence of the two groups were compared.Results Four weeks after surgery,the total clinical efficacy in the observation group(93.33%)was significantly higher than that of the control group(86.67%),while the SNOT-20 score in the observation group was lower(P=0.02).The Lund-Kennedy and Lund-Mackay scores in the observation group were lower(P=0.04,0.03);the recurrence rate was not statistically different between the two groups(P=0.27).Conclusion Implantation of drug sustained-release stent in the nasal sinus in functional endoscopic sinus surgery has a significant effect in the short-term for the treatment of refractory sinusitis,which can effectively improve the morphology of nasal mucosa,improve the quality of life,and result in fewer complications.
Drug sustained release stent implantationRefractory sinusitisFunctional endoscopic sinus surgerySinus mucosaComplications
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