Effects of H-UPPP combined with radiofrequency ablation of tongue root with low temperature plasma on oxygen saturation and arterial oxygen partial pressure in patients with OSAHS
Objective To explore the effect of han-uvulopalatopharyngoplasty(H-UPPP)combined with radiofrequency ablation of tongue root at low temperature on oxygen saturation and arterial partial pressure of oxygen(PaO2)in patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods Seventy-two patients with OSAHS were selected.They were divided into H-UPPP operation group(treated with single H-UPPP)and combined operation group(treated with H-UPPP combined with low-temperature plasma radiofrequency ablation of tongue root)according to the operation methods.Two patients were lost to follow-up,and finally 70 patients were included in this study.There were 35 patients in H-UPPP operation group and 35 patients in combined operation group.The apnea hypopnea index(AHI),low est oxygen saturation(LSaO2),PaO2,arterial partial pressure of carbon dioxide(PaCO2),forced vital capacity,forced expiratory volume in the first second,Epworth sleepiness scale(ESS)and visual analogue scale(VAS)were compared between the two groups before and 6 months after operation.The clinical efficacy and postoperative ad-verse reactions of the two groups were observed.Results Six months after operation,AHI and PaCO2 in the combined operation group and H-UPPP operation group decreased compared with that before operation,while LSaO2 and PaO2 increased(all P<0.05).The AHI of combined operation group was lower than that of H-UPPP operation group,and LSaO2,PaO2 were higher than that of H-UPPP operation group(P=0.036,0.030,0.001).But there was no significant difference in PaCO2 between the two groups at six months after operation(P=0.737).The forced vital capacity and forced expiratory volume in the first second in the combined opera-tion group and H-UPPP operation group were higher than those before operation(all P<0.05).The forced vital capacity and forced expiratory volume in the combined operation group were higher than those in the H-UPPP operation group(all P<0.001).The ESS score decreased and the VAS score increased in both groups.The ESS score of combined operation group was lower than that of H-UPPP operation group,and the VAS score was higher than that of H-UPPP operation group.The total effective rate of the combined operation group was higher than that of the H-UPPP operation group(P=0.025).There was no significant difference in the total in-cidence of postoperative complications between the two groups(P=0.353).Conclusion H-UPPP combined with radiofrequency ab-lation of tongue root with low temperature plasma can effectively promote the recovery of lung function and improve LSaO2,PaCO2,and PaO2 in patients with OSAHS,with good clinical efficacy and safety.
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