过敏性鼻炎与儿童新冠病毒肺炎感染及症状的关联性研究
Study on the correlation between allergic rhinitis and coronavirus disease-2019 infection and symptoms in children
张杰 1陈敏 2申征征 3吴宇华 3刘原虎 2孙浩 3谭新华 3倪树仁 3杨书勋 3史雪峥 3倪鑫2
作者信息
- 1. 国家儿童医学中心/首都医科大学附属北京儿童医院 耳鼻咽喉头颈外科,北京 100045;北京儿童医院顺义妇儿医院 耳鼻咽喉头颈外科,北京 101300
- 2. 国家儿童医学中心/首都医科大学附属北京儿童医院 耳鼻咽喉头颈外科,北京 100045
- 3. 北京儿童医院顺义妇儿医院 耳鼻咽喉头颈外科,北京 101300
- 折叠
摘要
目的 探究过敏性鼻炎对儿童新冠病毒肺炎(corona virus disease 2019,COVID-19)感染的影响.方法 回顾性分析205 例门诊患儿,使用问卷表收集一般情况、过敏性鼻炎、COVID-19 感染的临床资料.用视觉模拟评分法对COVID-19 感染后各部位症状进行评分.通过比较COVID-19 感染组与非感染组在性别、年龄、过敏性鼻炎方面的差异,通过线性回归分析感染组中症状轻重的影响因素.结果 COVID-19 感染与年龄、性别、过敏性鼻炎等因素无关.152 例COVID-19 感染患儿中,年龄与全身症状、咽喉部症状评分呈正相关.非过敏性患儿与过敏性鼻炎患儿COVID-19 感染的症状得分没有统计学差异.结论 过敏性鼻炎对儿童人群COVID-19 感染和症状轻重的影响很小,且对感染后的病程长短几乎没有影响.儿童COVID-19 患者在全身症状、咽喉部症状的程度与年龄呈正相关.
Abstract
Objective This study examined the potential impact of allergic rhinitis on children's susceptibility to and experience of coronavirus disease-2019(COVID-19)infection.Methods A retrospective analysis was conducted on 205 outpatients.Clinical data were collected through a questionnaire that assessed general information,presence of allergic rhinitis,and COVID-19 infection status.A visual analog scale was used to score the severity of COVID-19 symptoms across body areas.Chi-square and non-paramet-ric tests were used to compare the differences in age,sex,and allergic rhinitis prevalence between the COVID-19 infection and non-infection groups.Linear regression analysis explored factors influencing symptom severity in the infection group.Results No signif-icant association was found between COVID-19 infection and age,sex,allergic rhinitis,or other factors.Among the 152 children infected with COVID-19,age showed a positive correlation between symptom scores between children with and without allergic rhinitis.Conclusion In children,allergic rhinitis appears to have minimal impact on COVID-19 infection susceptibility,symptoms severity,or disease duration.While age demonstrated a positive correlation to the severity of throat symptoms in children with COVID-19,allergic rhinitis status was not a significant factor.
关键词
儿童COVID-19/过敏性鼻炎/影响因素/年龄/血管紧张素转化酶2Key words
Pediatric COVID-19/Allergic rhinitis/Influencing factors/Age/Angiotensin converting enzyme 2引用本文复制引用
出版年
2024
NETL
NSTL
万方数据