Formation mechanism and cyst fluid composition analysis of nasal mucosal cysts after functional endoscopy sinus surgery
Objective The objective of this study was to investigate the formatting factors and histological characteristics of nasal mucosal vesicles that commonly occurred in the nasal cavity after functional endoscopy sinus surgery(FESS).Methods We col-lected 10 cases of nasal mucosal vesicles from the nasal cavity of the patients with chronic rhinosinusitis after FESS.Vesicle tissues were assayed by histomorphological analysis and scanning electron microscope.The consistency of the liquid in the vesicles was examined by biochemistry analysis.Results Compared to normal mucosa,there were statistically significant differences in the proliferation of the epithelial layer(P=0.023)and the degree of infiltration of inflammatory cells(P=0.029)in the vesicles.At the same time,there was no statistically significant difference in the number of mucosal glands(P=0.631).The levels of lactate dehydrogenase(P＜0.001)and alanine transaminase(P＜0.001)in the vesicular fluid were significantly higher than their levels in the blood.As for aspartate transaminase(P＜0.001)and total protein(P=0.001),there were statistically significant decreases.Conclusion Nasal mucosal cysts occurring after FESS are composed of edematous mucosa,local infiltration of inflammatory cells,and exudate.A large amount of LDH and the increased AST level in the vesicle fluid suggested that the vesicles were related to sur-gical trauma.The vesicles that do not obstruct the ventilation and drainage of the surgical cavity do not need to be treated.The post-operative comprehensive treatment should be strengthened.
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