Mild cognitive impairment(MCI)serves as a transitional state between the typical ageing process and the onset of Alzhei-mer's disease.Emerging research indicates that MCI patients exhibit pathological alterations such as olfactory bulb atrophy and neuro-nal loss.Moreover,the severity of these pathological changes correlates with the degree of cognitive impairment.Hence,olfactory testing holds potential as a supplementary tool for MCI screening.Despite being in its nascent stages in China,research on early MCI diagnosis through olfactory tests is gaining momentum.In this study,we conduct a comprehensive review of pertinent literature,encompassing olfactory function,test content,characteristics,and current applications.Our aim is to furnish healthcare practitioners with insights into selecting suitable olfactory test instruments to enhance the early detection rate of MCI.
Mild cognitive impairmentOlfactoryOlfactory test instrumentsBulb atrophyNeuronal loss