New progresses in ovarian tissue cryopreservation and transplantation
Ovarian tissue cryopreservation and transplantation not only protect female fertility but also preserve ovarian endocrine function.It is effective in the prevention and treatment of iatrogenic premature ovarian insufficiency,especially in prepubertal girls and women in urgent need of disease treatment.The efficacy and safety of ovarian tissue cryopreservation have proved,and the current clinical gold standard is slow freezing,while vitrification is only for research.Despite the rapid development of this technique in recent years,it still faces problems such as cryoinjury,toxicity of cryoprotectants,assessment of follicular reserve,and safety of cryopreservation and transplantation.This article summarizes the progresses of research on these issues.
ovarian tissue cryopreservation and transplantationcryoinjuryfollicular reservesafety
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