基于"主客交"理论探析艾滋病发热病机及辨治思路

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中文摘要："主客交"理论出自吴有性《温疫论》,原用于指导温疫病的治疗,经后世医家补充发展,现多用于指导临床正虚邪恋之痼疾的治疗.艾滋病发热是人体感染人类免疫缺陷病毒(HIV)后,免疫功能被破坏,出现的各种机会性感染及肿瘤引起的一种常见临床症状.艾滋病发热的发生发展与"主客交"理论中正虚邪恋、外邪胶结于血脉、主客交浑的病机特点相似,故从"主客交"理论切入,探讨艾滋病发热的病机和辨治思路.认为肺卫不固,不能抵御外邪;脾气虚弱、气血津液耗伤、艾毒稽留、内生病理产物郁积,正气无力透邪为艾滋病发热的主要病机.在吴有性所创三甲散和"扶正祛邪,分离主客"治疗原则启示下,提出辨治艾滋病发热的思路,即透邪外出,引客离主;抓住本质,勿忘扶正;补托并用,分离主客.

外文标题：Pathogenesis and Treatment of AIDS Related Fever Based on Theory of "Host-Guest Interaction"

外文摘要：The theory of"host-guest interaction"originated from WU Youxing's Treatise on Warm Epidemic,which was originally used to guide the treatment of warm epidemic diseases.After the supplement and development of later doctors,it is now mostly used to guide the clinical treatment of chronic diseases of healthy qi deficiency and excessive pathogenic factors.AIDS related fever is a common clinical symptom caused by various opportunistic infections and tumors after the human body is infected with human immunodeficiency virus(HIV)and the immune function is destroyed.The occurrence and develop-ment of AIDS related fever are similar to the pathogenesis characteristics of healthy qi deficiency and excessive pathogenic factors,the adhesion of external pathogen in blood vessel and the interaction between host and guest in the theory of"host-guest interaction".Therefore,the pathogenesis and treatment of AIDS related fever are discussed from the theory of"host-guest interaction".It is believed that insecurity of lung-defense can not resist external pathogen.Spleen qi deficiency,depletion of qi,blood and body fluids,persistence of HIV,accumulation of endogenous pathological products,and inability of healthy qi to expel pathogenic factors are the main pathogenesis of AIDS related fever.Under the enlightenment of Sanjia Powder(三甲散)created by WU Youxing and the treatment principle of"reinforcing healthy qi and expelling pathogenic factors,separating host and guest",the authors put forward the idea of differentiating and treating AIDS related fever,that is,expelling pathogen and leading guest from host,grasping essence and reinforcing healthy qi,simultaneous tonifying and expressing,and separating host and guest.

外文关键词：

host-guest interactionAIDSfeverpathogenesisidea of differentiation and treatmentopportunistic infectionTreatise on Warm Epidemic

作者：

陈守生、李鹏宇、徐赫文、郭会军

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作者单位：

河南中医药大学,河南郑州 450046

河南中医药大学第一附属医院,河南郑州 450099

河南省病毒性疾病中医药防治重点实验室,河南郑州 450099

关键词：

主客交艾滋病发热病机辨治思路机会性感染《温疫论》

基金：

国家自然科学基金中原领军人才项目河南省科技攻关项目河南省中医药科学研究专项河南省国家中医药传承创新中心科研专项

项目编号：

82274474ZYYCYU2020121192321023112072022ZY10422023ZXZX1059

出版年：

2024

DOI：

10.16294/j.cnki.1007-659x.2024.01.004

山东中医药大学学报

山东中医药大学

山东中医药大学学报

CSTPCD

影响因子：0.52

ISSN：1007-659X

年,卷(期)：2024.48(1)

参考文献量36