首页|基于正交试验设计-组合赋权TOPSIS法的菟丝子酒炙工艺优化

基于正交试验设计-组合赋权TOPSIS法的菟丝子酒炙工艺优化

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目的:优选菟丝子酒炙炮制工艺,为规范酒菟丝子炮制工艺提供参考.方法:基于L9(34)正交试验设计,以饮片外观性状、金丝桃苷含量、总黄酮含量、醇溶性浸出物含量为指标,以加酒量(A)、闷润时间(B)、炒制温度(C)、炒制时间(D)为考察因素,采用层次分析法(AHP)结合熵权法的组合赋权方式计算综合评分,利用逼近理想解排序(TOPSIS)模型筛选出酒菟丝子炮制的最佳工艺参数并进行工艺验证.结果:筛选出最优炮制工艺为生药材加10%黄酒,闷润6 h,炒炙温度为300 ℃,炒炙10 min.结论:运用正交试验设计-组合赋权TOPSIS法优选菟丝子酒炙工艺,结果简便、准确、可行.
Optimization of Rice Wine Processing Technology of Tusizi(Cuscutae Semen)Based on Orthogonal Experimental Design-Combination Weighting TOPSIS Method
Objective:To optimize the rice wine processing technology of Tusizi(Cuscutae Semen),to provid a reference for regulating the rice wine processing technology of Tusizi.Methods:Based on the L9(34)orthogonal experimental design,the appearance properties,hypericin content,total flavone content and alcohol-soluble extract content of the decoction pieces were taken as indicators,and the amount of rice wine(A),moistening time(B),roasting tempera-ture(C)and roasting time(D)were taken as factors.The comprehensive score was calculated using the combination weighting method of analytic hierarchy process(AHP)and entropy weight method.The optimal rice wine processing parameters of Tusizi were selected and verified by technique for order preference by similarity to an ideal solution(TOPSIS)model.Results:The optimum processing technology was as follows:raw medicinal material of Tusizi was added with 10%rice wine,moistened for 6 h,with roasting temperature 300 ℃ and roasting time 10 min.Conclusion:The method of orthogonal experimental design and combination weighting TOPSIS method was used to optimize the rice wine processing technology of Tusizi.The results were simple,accurate and feasible.

Tusizi(Cuscutae Semen)processed with rice wineorthogonal testcombination weightingtechnique for order preference similarity to an ideal solution(TOPSIS)modelprocess optimization

张秀如、杨金平、焦春梅、崔雅晴、张翠翠、于明、林慧彬

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山东中医药大学,山东济南 250355

滨州市人民医院,山东滨州 256610

山东省农业广播电视学校平阴分校,山东济南 250499

山东省医药行业协会,山东济南 250013

山东省中医药研究院,山东济南 250014

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酒菟丝子 正交试验 组合赋权 逼近理想解排序模型 工艺优化

2024

山东中医药大学学报
山东中医药大学

山东中医药大学学报

CSTPCD
影响因子:0.52
ISSN:1007-659X
年,卷(期):2024.48(5)