Effects of Catgut Embedding Therapy at Eight Acupoints Around Umbilicus on Outcome of IVF-ET Treatment for Infertility Patients with Obese Polycystic Ovary Syndrome
Objective:To investigate the effect of catgut embedding therapy at eight acupoints around the umbilicus on the outcome of in vitro fertilization-embryo transfer(IVF-ET)treatment for obese poly-cystic ovary syndrome(PCOS)infertility patients.Methods:A total of 90 obese PCOS infertility patients were divided into the observation group and the control group by using random number table method,with 45 cases in each group.The control group received IVF-ET treatment,and the observation group received catgut embedding therapy at eight acupoints around the umbilicus combined with IVF-ET treatment.Statin B(INHB),luteinizing hormone(LH),testosterone(T),follicle-stimulating hormone(FSH),retinol-binding protein 4(RBP-4),albumin(Asprosin),leptin(LEP),adiponectin(APN),interleukin-17(IL-17),cholesterol(TC),and triglyceride(TG)of patients were detected before and after treatment.End-diastolic flow rate(EDV),maximum systolic flow rate(PSV)and resistance index(RI)of ovarian stroma hemodynamic indexes were recorded.The dosage of gonadotropin(Gn),number of follicles,M Ⅱ egg rate,fertilization rate,good embryo rate,clinical pregnancy rate and abortion rate were obtained.Results:After treatment,the levels of INHB,T,LH,TC,TG,Asprosin,RBP-4,LEP and IL-17 in two groups were lower than those before treatment,while the levels of FSH and APN were higher than those before treatment(P＜0.05).The levels of INHB,T,LH,TC,TG,Asprosin,RBP-4,LEP and IL-17 in the observation group were lower than those in the control group,and the levels of FSH and APN were higher than those in the control group(P＜0.05).After treatment,EDV and RI levels were decreased and PSV level was increased in both groups(P＜0.05),and EDV and RI levels in the observation group were lower than those in the control group,while PSV level was higher than that in the control group(P＜0.05).The dose of Gn in the observation group was less than that in the con-trol group(P＜0.05),the number of follicles obtained was more than that in the control group(P＜0.05),and the fertilization rate,M Ⅱ egg rate and clinical pregnancy rate were higher than those in the control group(P＜0.05).Conclusion:Catgut embedding therapy at eight acupoints around the umbilicus of obese PCOS infertility patients undergoing IVF-ET can improve sex hormone indexes,regulate ovarian reserve function and stromal hemodynamics,improve glucose and lipid metabolism and insulin sensitivity,inhibit body inflammation,which are beneficial for patients to obtain follicles and improve the pregnancy outcomes.
catgut embedding therapy at eight acupoints around the umbilicusinfertility with obese polycystic ovary syndromein vitro fertilization-embryo transferovarian reserve functionglucose and lipid metabolism
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