Objective:To explore the efficacy and mechanism of eye peripheral transcutaneous electrical acupoint stimulation device(Eye-TEAS)in preventing and treating myopia in children based on optical coherence tomography angiography(OCTA).Methods:Total 60 myopic children were included,the level of ocular parameters such as subfoveal choroidal thickness(SFCT)of the macular center pits were recorded and correlation analysis was performed for each parameter.And Eye-TEAS was used to intervene in the subjects for 3 months with 30 min per day,which was no less than 5 times per week.The changes of the subjects'spherical equivalent refraction(SER),axial length(AL),SFCT,and the vessel density of large vessels in the choroid(CVD)and the vessel density of the choroidal capillaries(CCVD)in the area of the macula measuring 3 mm × 3 mm were observed before the Eye-TEAS intervention,after the first intervention,after 1 month,and after 3 months of the intervention.Results:Total 58 myopic children completed the intervention and follow-up.In the baseline data observation,SER was significantly positively correlated with SFCT and CCVD(P＜0.01),while AL was significantly negatively correlated with SER,SFCT,CVD and CCVD(P＜0.05 or P＜0.01).Compared with the pre-intervention period,there were no significant changes in SER and AL after the first intervention,after 1 month,and after 3 months.There was no statistically significant difference between SFCT and baseline level after the first intervention(P＞0.05).There were statistically significant differences between SFCT and baseline level after 1 month and 3 months of intervention(P＜0.05).There was a significant positive correlation between SER changes and SFCT changes after 1 month of intervention(P＜0.05).CVD increased at the first intervention and 1 month after intervention(P＜0.05),but there was no statistically significant difference between CVD and baseline level after 3 months of intervention(P＞0.05).Compared with baseline data,CCVD significantly increased at 1 month and 3 months after intervention(P＜0.01).Conclusions:SFCT and fundus microcirculation in myopic children are highly correlated with AL and SER.After the intervention of Eye-TEAS,SFCT thickens significantly,and CVD and CCVD also increase significantly,which may be related to the fact that Eye-TEAS slows down the progression of myopia by affecting the changes in choroidal blood flow.
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