Correlation Between Traditional Chinese Medicine Syndromes and Dysosmia in Parkinson's Disease
Objective:To explore the correlation between traditional Chinese medicine(TCM)syndromes and dysosmia in patients with Parkinson's disease(PD).Methods:From October 2020 to December 2022 108 patients with PD were included randomly."Sniffin'Sticks"odor identification test(SS-16),Hoehn-Yahr(H-Y)staging,MoCA score,MDS-UPDRS Ⅲ were applied to evaluate patients.These patients were divided into normal olfactory group and dysosmia group according to the SS-16 test results.Results:The incidence of dysosmia in patients with PD was 65.7％.There were statistically significant differences in age(P=0.006),H-Y staging(P=0.012),MoCA score(P=0.016)and MDS-UPDRS Ⅲ scores(P=0.010)between the two groups.Binary Logistic regression analysis indicated that there was a significant correlation between dysosmia and gender(OR=3.504,P=0.023).There was a significant difference in TCM syndrome distribution between the dysosmia group and the normal olfactory group(P=0.017).Disordered multiple logistic regression analysis suggested that the presence or absence of olfactory dysfunction in patients(OR=9.047,P=0.018)affects the diagnosis of blood stasis with wind stirring syndrome and liver and kidney deficiency syndrome;The MoCA score(OR=1.146,P=0.046)affected the diagnosis of both qi and blood deficiency syndrome and liver and kidney deficiency syndrome in patients.Conclusions:There are differences in TCM syndromes between the dysosmia group and the olfactory normal group.The dysosmia affects the diagnosis of both blood stasis with wind stirring syndrome and liver and kidney deficiency syndrome in patients.
Parkinson's diseasedysosmiatraditional Chinese medicine syndromegenderMoCA score
万方数据
维普
