首页|参芪地黄汤合多靶点免疫抑制治疗IgA肾病合并膜性肾病个案报道

参芪地黄汤合多靶点免疫抑制治疗IgA肾病合并膜性肾病个案报道

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报道1例IgA肾病重复肾活检为IgA肾病合并膜性肾病的病例。患者病史长达11年且多种免疫抑制治疗均疗效不佳，属于难治性肾病，临床主要表现为大量蛋白尿及肾功能异常，伴有血尿、高血压。李伟教授根据多年用药经验及相关文献研究结果，给予参芪地黄汤联合多靶点免疫抑制治疗，重点分析中医辨证论治同西医病理结合，以益气活血清泄为原则，探讨其治疗方案及疾病转归，并复习相关文献，为中西医结合诊治IgA肾病合并膜性肾病提供治疗方向和临床依据。
Case Report of Shenqi Dihuang Decoction(参芪地黄汤)Combined with Multi-target Immunosuppression in Treatment of IgA Nephropathy and Membranous Nephropathy
One case of IgA nephropathy with membranous nephropathy after repeated renal biopsy was reported in this paper.The patient has a history of up to 11 years,and many immunotherapies were of poor curative effect.It is a refractory nephropathy.Major clinical manifestations are massive proteinuria and abnormal renal function,accompanied by hemuria and hypertension.Professor LI Wei prescribed Shenqi Dihuang Decoction(参芪地黄汤)combined with multi-target immunosuppression treatment according to years of clinical experience and relevant literature research results,focusing on the analysis of the combination of traditional Chinese medicine syndrome differentiation and pathology of western medicine.Based on the principle of supplementing qi,activating blood and clearing,the treatment protocol and disease outcome were discussed,and the related literature was reviewed,so as to provide a treatment direction and clinical basis for the diagnosis and treatment of IgA nephropathy complicated with mem-branous nephropathy.

IgA nephropathymembranous nephropathyShenqi Dihuang Decoctionmulti-target immunosup-pressionsupplementing qiactivating blood and clearing

兰明希、周乐、高冉冉、韩聪、李伟

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山东中医药大学,山东济南 250355

山东中医药大学附属医院,山东济南 250014

IgA肾病 膜性肾病 参芪地黄汤 多靶点免疫抑制 益气 活血清泄

国家自然科学基金项目国家自然科学基金青年科学基金项目山东省自然科学基金项目山东省中医药科技项目

8217417982204886ZR2021LZY0412020Q012

2024

10.16295/j.cnki.0257-358x.2024.04.018

山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子：0.431
ISSN：0257-358X
年,卷(期)：2024.43(4)
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