首页|天麻钩藤饮加减联合电针治疗急性脑梗死下肢偏瘫合并高血压临床研究

天麻钩藤饮加减联合电针治疗急性脑梗死下肢偏瘫合并高血压临床研究

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目的:观察天麻钩藤饮加减联合电针对急性脑梗死下肢偏瘫合并高血压患者偏侧下肢神经功能及血流变化的影响。方法:收集肝阳上亢型急性脑梗死下肢偏瘫合并高血压患者242例,采用随机数字表法分为基础治疗组62例、中药组61例、电针组58例、联合组61例,基础治疗组给予降压、抗血小板、降脂稳斑、改善循环、清除自由基等基础治疗,在此基础上,中药组加服天麻钩藤饮加减方,电针组加用电针治疗,联合组同时加以天麻钩藤饮加减方及电针治疗。治疗2周、4周后分别对患侧下肢运动功能、感觉功能、平衡功能进行评估,同时记录患侧下肢胫后(PT)动脉峰值流速、足背(DP)动脉峰值流速,评估患者下肢神经功能和血流变化情况。结果:重复测量方差分析显示,治疗后,各组患者下肢运动功能、平衡功能、感觉功能、PT动脉峰值流速、DP动脉峰值流速均较治疗前有所改善(P<0。05)。析因设计方差分析显示,治疗2周、4周后,中药组、电针组运动功能均有明显改善(P<0。05);治疗4周后电针组感觉功能明显改善(P<0。05),中药组平衡功能显著改善(P<0。05);治疗2周、4周后中药组PT、DP动脉峰值流速均明显改善(P<0。05),电针组未见明显变化(P>0。05)。结论:天麻钩藤饮加减方联合电针治疗可明显改善患者下肢运动功能、感觉功能及平衡功能,提高下肢动脉峰值流速,有效改善急性脑梗死患者患侧下肢的神经功能及循环功能。
Clinical Study on Modified Tianma Gouteng Decoction(天麻钩藤饮)Combined with Electroacupuncture in Treatment of Acute Cerebral Infarction with Lower Limb Hemiplegia Complicated with Hypertension
Objective:To observe the effect of Modified Tianma Gouteng Decoction(天麻钩藤饮)combined with electroacupuncture on the neurological function and blood flow of lower limb on the affected side in patients with acute cerebral infarction with lower limb hemiplegia complicated with hypertension.Methods:A total of 242 patients with acute cerebral infarction with lower limb hemiplegia complicated with hypertension of upper hyperactivity of liver yang were collected and divided into the basic treatment group(62 cases),the Chinese medicine group(61 cases),the electroacupuncture group(58 cases),and the combination group(61 cases)by using random number table method.The basic treatment group was given basic treatments such as antihypertensive,anti-platelet,lipid-lowering and plaque stabilizing,improving circulation and removing free radicals.On this basis,the Chinese medicine group was given Modified Tianma Gouteng Decoction,the electroacupuncture group was given electroacupuncture treatment,and the combination group was given Modified Tianma Gouteng Decoction combined with electroacupuncture treatment.After 2 weeks and 4 weeks of treatment,the motor function,sensory function and balance function of the lower limb on the affected side were evaluated,and the peak arterial flow velocity of the posterior tibial(PT)and dorsalis pedis(DP)of the lower limb were recorded,and the changes of nerve function and blood flow of the lower limb were evaluated.Results:Repeated mea-surement analysis of variance(ANOVA)showed that,after treatment,the lower limb motor function,balance function,sensory function,peak flow velocity of the PT and DP arteries in each group were improved compared with those before treatment(P<0.05).Factorial design ANOVA showed that,after 2 weeks and 4 weeks of treatment,the motor function of Chinese medicine group and electroacupuncture group were significantly improved(P<0.05);After 4 weeks of treatment,the sensory function in the electroacupuncture group was significantly improved(P<0.05),and the balance function in the Chinese medicine group was significantly improved(P<0.05);After 2 weeks and 4 weeks of treatment,the peak flow velocity of PT and DP arteries in the Chinese medicine group were significantly improved(P<0.05),while there was no significant change in the electroacupuncture group(P>0.05).Conclusion:Modified Tianma Gouteng Decoction combined with electroacupuncture can significantly improve the lower limb motor function,sensory function and balance function,increase the peak flow velocity of lower limb arteries,and effectively improve the nerve function and circulatory function of the lower limb in patients with acute cerebral infarction.

upper hyperactivity of liver yangacute cerebral infarctionhypertensionlower limb hemiplegiaTianma Gouteng Decoctionelectroacupuncturenerve functioncircular function

杨莹、闫俊、乔琳、叶楠、高亚亚、郭华、黄家欣、职利琴

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西安市第五医院,陕西西安 710082

肝阳上亢 急性脑梗死 高血压 下肢偏瘫 天麻钩藤饮 电针 神经功能 循环功能

陕西省中医药局科研项目陕西省中医药局科研项目陕西省中医药局科研项目西安市创新能力强基计划

SZY-KJCYC-2023-082SZY-NLTL-2024-02SZY-NLTL-2024-01621YXYJ0052

2024

山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子:0.431
ISSN:0257-358X
年,卷(期):2024.43(5)
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