首页|黄鱼清热宣肺方对早期肺癌患者胸腔镜术后康复的影响

黄鱼清热宣肺方对早期肺癌患者胸腔镜术后康复的影响

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目的:探讨黄鱼清热宣肺方对早期肺癌患者胸腔镜术后康复的影响。方法:选取早期肺癌患者200例,根据随机数字表法分别为对照组、中药组各100例。两组均予单孔胸腔镜下肺癌切除手术,对照组采用常规治疗,中药组在常规治疗基础上以黄鱼清热宣肺方加减治疗。比较两组术后胸腔引流管留置时间、胸水总引流量,住院费用、术后住院时间,术前及术后第1天、第5天的炎症反应指标,术后第1、3、5天手术切口疼痛评分及术后呼吸困难指数(mMRC)。结果:两组术后胸腔引流管留置时间、胸水总引流量比较,差异无统计学意义(P>0。05),中药组患者住院费用、手术后住院时间均低于对照组(P<0。05)。与术前比较,两组术后红细胞沉降率(ESR)水平均呈持续升高趋势(P<0。05),其他炎症指标均先升高后降低(P<0。05);术后第5天,中药组降钙素原(PCT)、白细胞(WBC)、白细胞介素-6(IL-6)、肿瘤坏死因子(TNF)、ESR水平均低于对照组(P<0。05)。两组患者术后手术切口疼痛评分及呼吸困难指数(mMRC)评分呈降低趋势(P<0。05),中药组术后第3天、第5天手术切口疼痛评分及mMRC评分均低于对照组(P<0。05)。结论:黄鱼清热宣肺方可有效减轻早期肺癌患者术后全身炎症反应,减少术后并发症,加速康复。
Effect of Huangyu Qingre Xuanfei Prescription(黄鱼清热宣肺方)on Postoperative Rehabilitation of Early Lung Cancer Patients After Thoracoscopic Surgery
Objective:To investigate the effect of Huangyu Qingre Xuanfei Prescription(黄鱼清热宣肺方)on the postoperative rehabilitation of early lung cancer patients after thoracoscopic surgery.Methods:A total of 200 patients with early lung cancer were selected and divided into the control group and the Chinese medicine group according to random number table method,with 100 patients in each group.Both groups received lung cancer resection surgery under single hole thoracoscopy.The control group was treated with conventional treatment,while the Chinese medicine group was treated with modified Huangyu Qingre Xuanfei Prescription on the basis of conventional treatment.The postoperative retention time of thoracic drainage tube,total drainage volume of pleural fluid,hospitalization cost,postoperative hospital stay,inflammatory response indexes before and on the 1st and 5th day after surgery,incision pain score and postoperative dyspnea index(mMRC)on the 1st,3rd and 5th day after surgery were compared between the two groups.Results:There was no significant difference in the retention time of thoracic drainage tube and total drainage volume of pleural fluid between the two groups(P>0.05).The hospitalization cost and postoperative hospitalization time in the Chinese medicine group were lower than those in the control group(P<0.05).Compared with the pre-operation,the postoperative cell sedimentation rate(ESR)levels in both groups showed a trend of continuous increase(P<0.05),and other inflammatory indicators were increased first and then decreased(P<0.05).On the fifth day after surgery,the levels of procalcitonin(PCT),white blood cell(WBC),interleukin 6(IL-6),tumor necrosis factor(TNF)and ESR in the Chinese medicine group were lower than those in the control group(P<0.05).Postoperative incision pain score and dyspnea index(mMRC)score of the two groups showed a decreasing trend(P<0.05).The incision pain score and mMRCT score of the Chinese medicine group were lower than those of the control group on the 3rd and 5th day after surgery(P<0.05).Conclusion:Huangyu Qingre Xuanfei Prescription can effectively reduce systemic inflammatory reaction,reduce postoperative complications and accelerate the rehabilitation of early lung cancer patients after thoracoscopic surgery.

early lung cancerafter thoracoscopic surgeryHuangyu Qingre Xuanfei Prescriptioninflammatory responsepostoperative rehabilitation

路雪雷、苏奎国、于士昌、翟建宾、赵臣亮、程志鸿、王崇礼、龚一非、赵亮

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河北中医学院第一附属医院心胸外科,河北石家庄 050011

早期肺癌 胸腔镜术后 黄鱼清热宣肺方 炎症反应 术后康复

河北省政府资助临床医学优秀人才培养项目

13000022P00DE34100247

2024

山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子:0.431
ISSN:0257-358X
年,卷(期):2024.43(5)
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