Effect of Huangyu Qingre Xuanfei Prescription(黄鱼清热宣肺方)on Postoperative Rehabilitation of Early Lung Cancer Patients After Thoracoscopic Surgery
Objective:To investigate the effect of Huangyu Qingre Xuanfei Prescription(黄鱼清热宣肺方)on the postoperative rehabilitation of early lung cancer patients after thoracoscopic surgery.Methods:A total of 200 patients with early lung cancer were selected and divided into the control group and the Chinese medicine group according to random number table method,with 100 patients in each group.Both groups received lung cancer resection surgery under single hole thoracoscopy.The control group was treated with conventional treatment,while the Chinese medicine group was treated with modified Huangyu Qingre Xuanfei Prescription on the basis of conventional treatment.The postoperative retention time of thoracic drainage tube,total drainage volume of pleural fluid,hospitalization cost,postoperative hospital stay,inflammatory response indexes before and on the 1st and 5th day after surgery,incision pain score and postoperative dyspnea index(mMRC)on the 1st,3rd and 5th day after surgery were compared between the two groups.Results:There was no significant difference in the retention time of thoracic drainage tube and total drainage volume of pleural fluid between the two groups(P>0.05).The hospitalization cost and postoperative hospitalization time in the Chinese medicine group were lower than those in the control group(P<0.05).Compared with the pre-operation,the postoperative cell sedimentation rate(ESR)levels in both groups showed a trend of continuous increase(P<0.05),and other inflammatory indicators were increased first and then decreased(P<0.05).On the fifth day after surgery,the levels of procalcitonin(PCT),white blood cell(WBC),interleukin 6(IL-6),tumor necrosis factor(TNF)and ESR in the Chinese medicine group were lower than those in the control group(P<0.05).Postoperative incision pain score and dyspnea index(mMRC)score of the two groups showed a decreasing trend(P<0.05).The incision pain score and mMRCT score of the Chinese medicine group were lower than those of the control group on the 3rd and 5th day after surgery(P<0.05).Conclusion:Huangyu Qingre Xuanfei Prescription can effectively reduce systemic inflammatory reaction,reduce postoperative complications and accelerate the rehabilitation of early lung cancer patients after thoracoscopic surgery.
early lung cancerafter thoracoscopic surgeryHuangyu Qingre Xuanfei Prescriptioninflammatory responsepostoperative rehabilitation