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当归化学成分及药理作用研究进展

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当归在补血药中因"补而不滞"的特点,被广泛用于临床。其化学成分主要包括挥发油类、多糖类、有机酸类、氨基酸类、黄酮类等,常用水蒸气蒸馏法、超临界CO2萃取法、有机溶剂萃取法、煎煮法、渗漉法、超声提取等方法进行提取,而炮制方式、地域、物候期、药用部位的不同皆可影响其化学成分。关于当归药理作用的研究亦愈发深入,当前已证实的包括调节血液循环、缺血后损伤保护、抗组织纤维化、镇痛、保护脑和神经、改善机体骨损伤状态、提高机体免疫力等。参考文献76篇。
Research Progress on Chemical Components and Pharmacological Effects of Danggui(Angelicae Sinensis Radix)
Danggui(Angelicae Sinensis Radix)is widely used in clinical practice because of the characteristics of"tonifying without stagnation"in blood tonics.Its chemical composition mainly includes volatile oils,polysaccharides,organic acids,amino acids,flavonoids,etc.,which are commonly extracted by steam distillation,supercritical CO2 extraction,organic solvent extraction,decoction,osmosis,ultrasonic extraction and other methods,and the chemical composition can be affected by the difference in processing methods,regions,phenological periods,and medicinal parts.The pharmacological effects of Danggui have also become more and more in-depth,and the current confirmed ones include regulating blood circulation,post-ischemic injury pro-tection,anti-tissue fibrosis,analgesia,protecting the brain and nerves,improving the body's bone injury state,and improving the body's immunity.There are 76 references.

Danggui(Angelicae Sinensis Radix)chemical componentsingredient extractionprocessing methodregionphenological periodmedicinal partpharmacological effect

牟春燕、殷越、沈子芯

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黑龙江中医药大学研究生院,黑龙江哈尔滨 150040

黑龙江中医药大学基础医学院,黑龙江哈尔滨 150040

当归 化学成分 成分提取 炮制方式 地域 物候期 药用部位 药理作用

黑龙江省博士后科研启动基金黑龙江省国医大师学术思想传承科研项目

LBH-Q20179GY2022-04

2024

山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子:0.431
ISSN:0257-358X
年,卷(期):2024.43(5)
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