Research Progress on Mechanisms of Modified Ditan Decoction(涤痰汤)in Treating Cerebral Ischemia-Reperfusion Injury
Ditan Decoction(涤痰汤)is a classic prescription for treating stroke,and clinical practice has shown that it has a significant improvement effect on cerebral ischemia-reperfusion injury.By reviewing relevant literature,it has been found that the mechanisms of modified Ditan Decoction in treating cerebral ischemia-reperfusion injury include inhibiting oxidative stress response,reducing inflammatory reaction,suppressing excitatory amino acid toxicity,inhibiting neuronal apoptosis,and regulating autophagy.These mechanisms work together to effectively protect neurons,reduce brain edema and hemorrhagic transformation,and improve symptoms of neurological functional deficits.In terms of individual medicinal components,the effects of the main components in each medicine align with those of the compound formula Ditan Decoction.There are 77 references.