首页|从"脾藏营舍意"论溃疡性结肠炎诱发抑郁的机制

从"脾藏营舍意"论溃疡性结肠炎诱发抑郁的机制

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"脾藏营舍意"首见于《灵枢·本神》，体现了脾运化水谷精微上输于脑以滋养"意"的功能。若是脾的功能受到损害，"意"的功能也将无法正常发挥。该病理理念与溃疡性结肠炎诱发抑郁的病理机制——肠道炎性反应中枢侵袭及其他一系列病理反应导致大脑海马损伤最终诱发抑郁行为的病理过程相合。阐释中医"脾藏营舍意"理论与溃疡性结肠炎诱发抑郁机制的相关性，以期将"脾藏营舍意"这一理论用于指导溃疡性结肠炎诱发抑郁的临床诊疗。
Discussion on Mechanism of Depression Induced by Ulcerative Colitis from Perspective of"Spleen Storing Nutrient and Housing Idea"
"Spleen storing nutrient and housing idea"is initially recorded in Miraculous Pivot-Roots of Spirit,which reflects the function of spleen in transporting and transforming the essence of water and grains to the brain to nourish the"idea".If the function of the spleen is damaged,the function of"idea"will not be able to exert.The concept of this pathology is consistent with the pathological mechanism of ulcerative colitis-induced depression——the intestinal inflammatory response invades the central nervous system and other series of pathological reactions lead to damage to the brain hippocampus and ultimately induce depressive-like behavior.This paper elucidates the correlation between the traditional Chinese medicine theory of"spleen storing nutrient and housing idea"and the mechanism of depression induced by ulcerative colitis,with a prospect of applying the theory of"spleen storing nutrient and housing idea"in guiding the clinical diagnosis and treatment of depression induced by ulcerative colitis.

ulcerative colitisdepressionspleen stor-ing nutrient and housing ideaclinical diagnosis and treatment

刘薇、田锋亮、曾健、袁玲、刘宇、邱红、路琼琼、徐健众

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重庆市中医院,重庆 400013

溃疡性结肠炎 抑郁 脾藏营舍意 临床诊疗

国家自然科学基金青年基金项目中国博士后科学基金面上项目重庆市自然科学基金博士后项目重庆市博士后研究项目特别资助二等资助重庆市科研机构绩效激励引导专项四川省科技厅区域创新合作项目

822050852023M7404372022NSCQ-BHX48792023CQBSHTB2042jxyn2021-1-122023YFQ0016

2024

10.16295/j.cnki.0257-358x.2024.08.008

山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子：0.431
ISSN：0257-358X
年,卷(期)：2024.43(8)
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