"Spleen storing nutrient and housing idea"is initially recorded in Miraculous Pivot-Roots of Spirit,which reflects the function of spleen in transporting and transforming the essence of water and grains to the brain to nourish the"idea".If the function of the spleen is damaged,the function of"idea"will not be able to exert.The concept of this pathology is consistent with the pathological mechanism of ulcerative colitis-induced depression——the intestinal inflammatory response invades the central nervous system and other series of pathological reactions lead to damage to the brain hippocampus and ultimately induce depressive-like behavior.This paper elucidates the correlation between the traditional Chinese medicine theory of"spleen storing nutrient and housing idea"and the mechanism of depression induced by ulcerative colitis,with a prospect of applying the theory of"spleen storing nutrient and housing idea"in guiding the clinical diagnosis and treatment of depression induced by ulcerative colitis.
关键词
溃疡性结肠炎/抑郁/脾藏营舍意/临床诊疗
Key words
ulcerative colitis/depression/spleen stor-ing nutrient and housing idea/clinical diagnosis and treatment