山东中医杂志2024,Vol.43Issue(9) :1024-1030.DOI:10.16295/j.cnki.0257-358x.2024.09.019

中医药治疗慢性淋巴细胞白血病及伊布替尼不良反应个案报道

Case Report of Traditional Chinese Medicine Treatment of Chronic Lymphocytic Leukemia and Adverse Effects of Ibrutinib

田文灏 马薇 何晓玉 石凤芹
山东中医杂志2024,Vol.43Issue(9) :1024-1030.DOI:10.16295/j.cnki.0257-358x.2024.09.019

中医药治疗慢性淋巴细胞白血病及伊布替尼不良反应个案报道

Case Report of Traditional Chinese Medicine Treatment of Chronic Lymphocytic Leukemia and Adverse Effects of Ibrutinib

田文灏 1马薇 2何晓玉 3石凤芹2
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作者信息

  • 1. 北京中医药大学第一临床医学院,北京 100029
  • 2. 北京中医药大学东直门医院血液肿瘤科,北京 100700
  • 3. 天津市第一中心医院中西医结合科,天津 300192
  • 折叠

摘要

回顾性分析北京中医药大学东直门医院收治的1例伊布替尼治疗慢性淋巴细胞白血病致肺部感染患者的临床资料,并复习相关文献.该患者在服用伊布替尼治疗时并发肺部感染,遂停药,结合中医药治疗后感染症状得到控制,后继续坚持口服中药治疗,慢性淋巴细胞白血病的相关症状得到改善,且未再发生感染.针对长时间应用伊布替尼治疗慢性淋巴细胞白血病的患者,需警惕肺部真菌感染的发生.中医药在治疗慢性淋巴细胞白血病中,能够防止各类感染的发生,提高机体耐受力,延长患者生存期.

Abstract

The clinical data of a patient with pulmonary infection caused by chronic lymphocytic leukemia treated with ibrutinib in Dongzhimen Hospital of Beijing University of Chinese Medicine were retrospectively analyzed,and the relevant literature was reviewed.The patient was complicated with pulmonary infection during ibrutinib treatment,so ibrutinib was stopped and traditional Chinese medicine treatment was combined,and the infection symptoms were controlled.After continued to adhere to oral tra-ditional Chinese medicine treatment,the symptoms related to chronic lymphocytic leukemia were relieved,and there was no recurrence of infection.For patients with chronic lymphocytic leukemia treated with ibrutinib for a long period of time,it is necessary to be alert to the occurrence of pulmonary fungal infection.Traditional Chinese medicine can prevent the occurrence of various infections,improve the body tolerance,prolong the survival of patients in the treatment of chronic lymphocytic leukemia.

关键词

中医药/伊布替尼/慢性淋巴细胞白血病/肺部感染

Key words

traditional Chinese medicine/ibrutinib/chronic lymphocytic leukemia/pulmonary infection

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基金项目

&&(202169-004)

出版年

2024
山东中医杂志
山东中医药学会 山东中医药大学

山东中医杂志

CSTPCD
影响因子:0.431
ISSN:0257-358X
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