Clinical Study on Treatment of Pediatric Anorexia with Combination of Kai Xuanji,Compound Manipulation "An Xian Cuo Mo" and Chinese Medicine
Objective:To observe the clinical curative efficacy of combination of Kai Xuanji,compound manipulation"An Xian Cuo Mo"and Chinese medicine in treatment of pediatric anorexia and its influence on serum gastrointestinal hormone,serum appetite-regulating factors levels and nutritional status of pediatric patients.Methods:A total of 84 children with anorexia were divided into the observation group and the control group by random number table method,with 42 cases in each group.The control group was treated with modified Buhuanjin Zhengqi Powder(不换金正气散),while the observation group received additional treatment with Kai Xuanji combined with compound massage"An Xian Cuo Mo"on the basis of the control group.The changes in traditional Chinese medicine(TCM)syndrome scores,serum levels of gastrointestinal hormones(motilin and gastrin),serum levels of appetite-regulating factors(neuropeptide Y,orexin,leptin),and nutritional status(blood zinc,calcium,hemoglobin)before and after treatment were observed in the two groups.The safety and curative efficacy of the treatments in the two groups were evaluated.Results:After treatment,the TCM syndrome scores and level of leptin in the two groups were lower than those before treatment(P＜0.05),and the TCM syndrome scores and level of serum leptin in the observation group were lower than those in the control group(P＜0.05).After treatment,the levels of serum motilin,gastrin,neuropeptide Y,orexin,blood zinc,calcium,and hemoglobin in the two groups all increased compared to before treatment(P＜0.05),with the observation group showing higher levels than the control group(P＜0.05).There were no severe adverse reations in the two groups during the treatment period.The total effective rate following treatment was higher in the observation group compared to the control group,and there was a statistically significant difference between the two groups(P＜0.05).Conclusions:The combination of Kai Xuanji,compound manipulation"An Xian Cuo Mo"and Chinese medicine for pediatric anorexia has definite curative efficacy,as it can reduce the TCM syndrome scores of affected children and improve the levels of serum gastrointestinal hormones,serum appetite-regulating factors,and nutritional status.
Kai xuanjicompound manipulation"An Xian Cuo Mo"Buhuanjin Zhengqi Powderpediatric anorexiagastrointestinal hormoneappetite-regulating factorsnutritional status
万方数据
维普
