ZHANG Yingwen's Experience in Treatment of Refractory Nephrotic Syndrome with Warming and Subduing Method
Professor ZHANG Yingwen believes that the core pathogenesis of refractory nephrotic syndrome(RNS)is the change of ministerial fire.Specifically,the pathogenesis of steroid-resistant RNS is characterized by turbid pathogens accumulating internally and hyperactivity of ministerial fire,while the pathogenesis of steroid-dependent RNS is characterized by decline of vital gate fire and excessive floating of ministerial fire.Therefore,she suggests using the warming and subduing method for treating RNS.The treatment of steroid-resistant RNS prioritizes methods such as clearing heat,promoting diuresis,activating blood circulation,and dispelling wind to eliminate pathogenic factors.It is supplemented with warming and nourishing kidney essence and blood,as well as subduing hyperactivity of ministerial fire.For steroid-dependent RNS,the treatment is based on a staged approach during the process of tapering off hormones to ensure the proper sequence of warm tonifying medicinals and medicinals that subdue excessive movement.One proved case is attached.
refractory nephrotic syndromeministerial firethe warming and subduing methodsteroid-resistantsteroid-dependent