Treatment of Severe Mucoid Pseudomonas Aeruginosa Pneumonia with Combination of Traditional Chinese and Western Medicine:A Case Report and Literature Review
In this article,the diagnosis and treatment process of a severe case of mucoid Pseudomonas aeruginosa pneumonia using both Chinese and western medicine is summarized.Additionally,the Chinese medical diagnostic and treatment approach for Pseudomonas aeruginosa pneumonia is analyzed and discussed.The patient came for consultation due to"repeated coughing,sputum production,and shortness of breath for over 10 years,with worsening symptoms in the past 10 days".The diagnosis was acute exacerbation of chronic obstructive pulmonary dis-ease(AECOPD)type Ⅱ respiratory failure,bronchial asthma,bronchiectasis,and type 2 diabetes.Conse-quently,the patient was admitted for treatment.After admission,due to the critical condition,endotracheal intubation was performed and a ventilator was used for respiratory support.Additionally,the anti-infective treatment was given because high-throughput gene sequencing of bronchoalveolar lavage fluid revealed a sequence count of 73 659 for Pseudomonas aeruginosa.After achieving a normal oxygenation index through the use of endotracheal intubation and assisted ventilation with a ventilator,the endotracheal tube is removed and high-flow humidified oxygen therapy is continued.Subsequently,the patient experienced recurrent rapid breathing,high fever,restlessness,accompanied by dry mouth and decreased sweating.Considering that the anti-infection treatment had lasted for nearly 2 weeks,there might be adverse reactions such as antibiotic-induced fever,so the use of antibiotics was temporarily suspended and traditional Chinese medicine treatments including Daqinglong Decoction(大青龙汤),Dachengqi Decoction(大承气汤),and Baihu Jia Renshen Decoction(白虎加人参汤)were successively applied.After treatment with traditional Chinese medicine,the patient's fever symptom gradually subsided.The sputum culture indicated mucoid Pseudomonas aeruginosa(sensitive to all antibiotics).Eventually,the condition stabilized and the patient was discharged.In the past,traditional Chinese medicine often used methods such as clearing lung and resolving phlegm,purging heat and promoting bowel movement to treat Pseudomonas aeruginosa infections,with less emphasis on reinforcing healthy qi.According to the treatment situation of the above case,the author believes that in the process of treating Pseudomonas aeruginosa pneumonia with traditional Chinese medicine,it is necessary to pay more attention to healthy qi and adjust the treatment plan timely based on the strength of healthy qi.
Pseudomonas aeruginosa pneumoniaDaqinglong DecoctionDachengqi DecoctionBaihu Jia Renshen Decoctionmedical case report