Exploring the Correlation Between Gut Microbiota Disorder and Sepsis Induced Acute Lung Injury from the Perspective of"Lung and Large Intestine"
The pathogenesis of acute lung injury caused by sepsis is complex,and the mortality rate is high,and there is currently a lack of targeted treatment methods.Intestinal flora disorders,which can participate in the occurrence and development of acute lung injury through the"intestine-lung axis".The paper interprets the basic theory of"lung being connected with large intestine"in traditional Chinese medicine through the modern medical understanding of intestinal flora,discusses the role of intestinal flora disturbance in the pathogenesis of acute lung injury in traditional Chinese medicine,takes"lung and intestine co-treat-ment"as the fundamental principle,proposes a new prevention and treatment strategy for acute lung injury with the improvement of intestinal ecological balance as the core,and clearly defines the stage treatment.In the early stage,the pathogenic factors are on the surface of the body,there are lung qi stagnation and intestinal collateral damage.The treatment mainly focuses on clearing heat,promoting lung function,moistening the lower-jiao and clearing fu-viscera,and promoting qi circulation,as well as eliminating carbuncle stagnation.In the middle stage,the pathogenic factors are intense and the intestines and organs are obstructed.The treatment is to detoxify and clear the lungs,drege the lower-jiao and clear fu-viscera,and cool blood and dissipate blood stasis.In the late stage,the blood is in extreme heat,the fluid dries up and the lung yin is depleted,the intestines stagnation is formed,and the syndrome of inversion is clustered.The treatment is to nourish yin and clear heat,open the fu-viscera,which is assisted by supporting the healthy qi and reversing qi.
acute lung injury caused by sepsisintestinal flora disterbancelung being connected with large intestineintestine-lung axislung and intestine co-treatment
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