Randomized Controlled Study on Roche Tri-sachet Combined with Western Medicine in Treatment of Mesenteric Lymphadenitis in Children
Objective:To observe the effect of Roche tri-sachet combined with western medicine in the treatment of children with mesenteric lymphadenitis.Methods:A total of 60 pediatria patients diagnosed with mesenteric lymphadenitis were divided into the treatment group and the control group according to random number table method,with 30 cases in each group.The control group was given the conventional oral probiotic Clostridium butyricum enterococcus triple viable tablets,200 mg/3 times a day for children over 5 years old and 100 mg/3 times a day for children under 5 years old,the treatment was for 4 weeks.The treatment group was given topical Roche tri-sachet[composition:Xiaohuixiang(Foeniculi Fructus)200 g,Ganjiang(Zingiberis Rhizoma)30 g,Huoxiang(Agache Rugosa)20 g,and Muxiang(Aucklandia Radix)30 g],placed on the lower abdomen of the children for treatment,15～20 min each time,twice a day,the dosage of which was the same as that of the control group,the treatment was for 4 weeks.The clinical efficacy,traditional Chinese medicine(TCM)syndrome score,symptom relief time,clinical indicators(white blood cells,Cardio Pulmonary Resuscitation,Procalcitonin),transverse and longitudinal diameter of retroperitoneal lymph nodes,immune function indicators(IgA,IgM,IgG),abdominal pain recurrence rate changes and adverse reactions were observed in the two groups to determine the efficacy of each group.Results:In the treatment group,the total effective rate was 96.7% ;in the control group the total effective rate was 83.3% ,the difference was statistically significant(P＜0.05).In the treatment group,the symptom remission time was shorter(P＜0.05),and the recurrence rate of abdominal pain was lower(P＜0.05).TCM syndrome scores and clinical indexes in the treatment group were lower than those in the control group(P＜0.05),transverse and longitudinal diameter of retroperitoneal lymph nodes were shorter(P＜0.05),and the immune function indexes were lower(P＜0.05).Conclusions:Roche tri-sachet combined with western medicine can relieve the clinical symptoms,reduce the recurrence rate of abdominal pain and have significant curative effec in the treatment of children with mesenteric lymphadenitis.
mesenteric lymphadenitis in childrenRoche tri-sachetclostridium butyricum,enterococcus saccharo-myces trifecta tabletsrandomized controlled study
万方数据
维普
