脉搏波速度、动脉弹性与冠心病影响因素的相关性
Correlation between pulse wave velocity, arterial elastic function and influencing factors of coronary heart disease
石姗姗 1李保应 1于飞 1王茜 1张志勉 2高海青1
作者信息
- 1. 山东大学齐鲁医院老年病科,济南250012
- 2. 山东大学齐鲁医院健康体检中心,济南250012
- 折叠
摘要
目的 研究颈-股脉搏波速度(CFPWV)、大动脉弹性指数(C1)、小动脉弹性指数(C2)和冠心病影响因素的相关性,并探讨CFFWV、C1、C2在冠心病早期诊断中的价值.方法 将131名受检者分为高血压组和高血压合并冠心病组,应用康普乐( Complior)动脉脉搏波速度测定仪(Artech,France)测定CFPWV,CV Profilor DO-2020型动脉弹性功能测定仪测定C1、C2.结果 ①与单纯高血压组相比,合并冠心病组的CFPWV、C1、C2均明显增高(P＜0.01)；②CFPWV与年龄、腔腹血糖(FPG)、甘油三酯(TG)、收缩压(SBP)、脉压(PP)呈正相关(r=0.475,0.186,0.183,0.360,0.455,P＜0.05),C1与年龄、SBP、PP呈负相关(r=-0.391,-0.247,-0.283,P＜0.01),C2与年龄、BMI、TG、SBP、PP、平均动脉压(MAP)呈负相关(r=-0.365,-0.126,-0.198,-0.340,-0.355,-0.210,P＜0.05).结论 CFPWV和C1、C2可作为早期预测冠心病的无创性敏感性指标.
Abstract
Objective To analyze the relationship between pulse wave velocity, arterial elastic indexes and cardiovascular risk factors in patients with coronary heart disease, and to find the value of carotid-femoral pulse wave velocity(CF-PWV) , large arteria elastic indexes(Cl) and small arterial elastic indexes(C2) in early diagnosis of coronary heart disease. Methods 131 subjects were divided into two groups;the hypertension group and the hypertension with coronary heart disease group. CFPWV, Cl and C2 were measured by the pulse wave velocity measurement system (Complior) and the artery elasticity function measurement system(CV Profilor DO-2020). Results ① The CFPWV, Cl and C2 of the coronary heart disease group were significantly higher than those of the hypertension group (P < 0.01). ② In multiple regression analysis, CFPWV was correlated with age, fasting blood sugar(FPG) , triglycerides(TG) , systolic blood pressure( SBP) and pulse pressure( PP) (r = 0.475, 0.186, 0.183, 0.360, 0.455, P <0.05 ). Cl was negatively correlated with age, SBP and PP(r = - 0.391, - 0.247, - 0.283, P < 0.01), and C2 was negatively correlated with age , body mass index(BMI), TG, SBP, PP and mean arterial pressure (MAP) (r = -0. 365, -0. 126, -0.198, -0.340, -0.355, -0. 210, P < 0.05). Conclusion CFPWV, Cl and C2 can be used as noninvasive and sensitive indicators for predicting coronary heart disease.
关键词
冠心病/脉搏波速度/大动脉弹性指数/小动脉弹性指数Key words
Coronary heart disease/Pulse wave velocity/Large arterial elastic indexes/Small arterial elastic indexes引用本文复制引用
出版年
2011
NETL
NSTL
维普
万方数据