大环内酯类抗生素治疗哮喘的研究进展
Research progress of the treatment of asthma with macrolide antibiotics
丁伊人 1刘婉莹 1姚蕾 1姚欣1
作者信息
- 1. 南京医科大学第一附属医院呼吸与危重症医学科,江苏南京 210029
- 折叠
摘要
哮喘是一种慢性气道炎症性疾病,吸入性糖皮质激素是其主要治疗药物.然而,少部分患者无法得到有效控制,对于此类患者亟需新的治疗方法.近年来,除了生物制剂的研究外,对于大环内酯类抗生素在哮喘治疗中的潜力也备受关注.本文就大环内酯类抗生素治疗哮喘的疗效、可能机制和不良反应进行系统综述.
Abstract
Asthma is a chronic inflammatory disease of the airways,and inhaled corticosteroids are the main treatment.However,a small number of patients cannot be effectively controlled,and new treatment methods are urgently needed for such patients.In recent years,in addition to the research on biological agents,there has been considerable interest in the therapeutic potential of macrolide antibiotics in asthma.This article provides a systematic review of the efficacy,possible mechanisms,and adverse reactions of macrolide antibiotics in the treatment of asthma.
关键词
肺疾病/支气管哮喘/大环内酯类抗生素/急性加重/治疗方法Key words
Pulmonary disease/Bronchial asthma/Macrolide antibiotics/Acute exacerbation/Treatment method引用本文复制引用
基金项目
呼吸疾病青年实用研究项目(Z-2017-24-2301)
出版年
2024
NETL
NSTL
万方数据