首页|大环内酯类抗生素治疗哮喘的研究进展

大环内酯类抗生素治疗哮喘的研究进展

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哮喘是一种慢性气道炎症性疾病,吸入性糖皮质激素是其主要治疗药物.然而,少部分患者无法得到有效控制,对于此类患者亟需新的治疗方法.近年来,除了生物制剂的研究外,对于大环内酯类抗生素在哮喘治疗中的潜力也备受关注.本文就大环内酯类抗生素治疗哮喘的疗效、可能机制和不良反应进行系统综述.
Research progress of the treatment of asthma with macrolide antibiotics
Asthma is a chronic inflammatory disease of the airways,and inhaled corticosteroids are the main treatment.However,a small number of patients cannot be effectively controlled,and new treatment methods are urgently needed for such patients.In recent years,in addition to the research on biological agents,there has been considerable interest in the therapeutic potential of macrolide antibiotics in asthma.This article provides a systematic review of the efficacy,possible mechanisms,and adverse reactions of macrolide antibiotics in the treatment of asthma.

Pulmonary diseaseBronchial asthmaMacrolide antibioticsAcute exacerbationTreatment method

丁伊人、刘婉莹、姚蕾、姚欣

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南京医科大学第一附属医院呼吸与危重症医学科,江苏南京 210029

肺疾病 支气管哮喘 大环内酯类抗生素 急性加重 治疗方法

呼吸疾病青年实用研究项目

Z-2017-24-2301

2024

山东大学学报(医学版)
山东大学

山东大学学报(医学版)

CSTPCD北大核心
影响因子:0.841
ISSN:1671-7554
年,卷(期):2024.62(5)