Research advances in Vitamin K2 and pregnancy-related diseases
Vitamin K2(VK2)is a vitamin that has been neglected for a long time.Recently,more and more evidences show that,in addition to the hepatic carboxylation of hemostatic related proteins,VK2 can play an important role in an-tioxidant,cardiovascular,bone metabolism and so on,which are closely related to pregnancy.Due to its possible defi-ciency status and good safety,VK2 has been added to some calcium supplements and multivitamin products used by pregnant women recently.However,to our knowledge,there is no review on the relationship between VK2 and pregnan-cy in the medical literature.This article aims to introduce the source and metabolic characteristics of VK2 in pregnancy,elaborate the possible relationship with pregnancy-specific diseases,evaluate the safety of supplementing VK2 in preg-nant women,in order to provide reasonable suggestions for the use of VK2 supplements in pregnancy.
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