Advances of metabolomics in airway inflammatory diseases
Airway inflammatory diseases,including allergic rhinitis,chronic sinusitis,asthma,and chronic obstructive pulmonary disease(COPD),are characterized by airway inflammation and airway hyperresponsiveness.Recently,metabolomics has emerged as a key tool for studying airway inflammatory diseases.Advances in analytical techniques are enhancing its sensitivity,accuracy,and throughput,offering deeper insights into metabolic changes in conditions like allergic rhinitis,asthma,and COPD.This review outlines advancements in metabolomics research on airway inflammatory diseases,and identifys metabolic pathways and products linked to inflammation and oxidative stress through analyses of blood,sputum,urine feces,and exhaled air condensate.It aims to guide precision medicine,en-hance understanding of disease mechanisms,identify biomarkers,evaluate treatment efficacy,and develop new therapies.
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