Esophageal cancer is a common malignancy in the digestive system,characterized by high in-cidence and mortality rates.Local recurrence or regional lymph node metastasis is common in clinical practice and is a major factor affecting the long-term survival of esophageal cancer patients.In recent years,Cy-berKnife,as a novel radiation therapy technique,has demonstrated potential advantages in the treatment of multiple tumor types,particularly in terms of local control and reducing adverse effects.This article aims to comprehensively analyze the application of CyberKnife in the treatment of esophageal cancer,to discuss its therapeutic effects and safety,and to explore future research directions.