Meta-analysis on the Relationship Between Lifestyle and Dietary Habits and the Risk of Oral Cancer
Objective To explore the relationship between personal lifestyle and dietary habits and the risk of oral cancer using evidence-based methods,aiming to establish a foundation for developing and implementing prevention and treatment strategies for oral cancer.Methods Articles regarding case-control studies on risk factors of oral cancer were retrieved from CNKI,VIP,Wanfang Data,Embase,PubMed and Cochrane Library from their establishment to October 2023.The Meta-analysis of the included articles was conducted using Rev-Man 5.3.Results A total of 16 articles were in-cluded,involving 5982 patients.Based on the Meta-analysis results,the protective factors of oral cancer included consuming fish[OR=0.55,95%CI(0.51,0.60)],consuming seafood[OR=0.49,95%CI(0.45,0.53)],consuming milk and dairy products[OR=0.60,95%CI(0.56,0.65)],consuming eggs[OR=0.71,95%CI(0.65,0.78)],consuming green vegetable[OR=0.28,95%CI(0.25,0.32)],consuming non-green vegetable[OR=0.34,95%CI(0.31,0.38)],consuming fruits[OR=0.32,95%CI(0.29,0.35)],supplementing vitamins[OR=0.40,95%CI(0.29,0.55)]and consuming healthcare products[OR=0.40,95%CI(0.30,0.53)](P<0.001 for all);the risk factors of oral cancer included consuming pickled products[OR=1.15,95%CI(1.05,1.25)],drinking alcohol[OR=2.05,95%CI(1.85,2.28)]and smoking[OR=1.87,95%CI(1.59,2.20)](P<0.01 for all).Conclusion Personal lifestyle and dietary habits are closely related to the incidence of oral cancer.Frequent consumption of fish,seafood,milk and dairy products,eggs,vegetables and fruits and supplementation of vitamins and healthcare products can reduce the risk of oral can-cer;however,frequent consumption of pickled products and alcohol and smoking can increase the risk of oral cancer.Healthcare providers should carry out targeted health education and intervention according to patients'conditions to reduce the risk of oral cancer.
万方数据
维普
