The present paper,analyzing in detail Lu Zhengxiang's attempt to fuse Confucian spiritual self-cultivation with Christian religious practice with a view to practically interconnecting theoretically irreconcilable ele-ments in Confucianism and Christianity,contends that Lu's religious practice helped researchers discuss the two teachings from religio-practical rather than from theoretical perspective and most importantly,this can be a historical reference inspiring the indigenization of religion in present-day China.