奎硫平合并利培酮治疗精神分裂症导致低血钾1例
Hypokalemia Caused by Quetiapine and Risperidone Treatment in Schizophrenia: A Case Report
杨琼玮 1郭晓云 2刘登堂2
作者信息
- 1. First-episode Schizophrenia and Early Psychosis Program, Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Minkang Hospital of Ningxia Civil Affairs Department, Ningxia, China
- 2. First-episode Schizophrenia and Early Psychosis Program, Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- 折叠
摘要
概述:低血钾可造成躯体多系统障碍,长期服用某些抗精神病药可能会导致电解质代谢的异常,包括血清钾的异常.我们报告一例49岁女性精神分裂症患者,在服用奎硫平和利培酮后出现低血钾,在换用其它抗精神病药(氨磺必利)后,血钾恢复正常.我们还讨论了抗精神病药导致低血钾的可能机制和临床注意事项.
Abstract
Hypokalemia can cause abnormalities in multiple systems.Long term use of antipsychotic medications can lead to electrolyte imbalance,including hypokalemia.We report a 49-year-old female patient with schizophrenia who developed hypokalemia after oral quetiapine and risperidone treatments.Her blood potassium became normal after she switched to another antipsychotic drug (amisulpride).In addition,we discuss the potential mechanism of antipsychotic drugs leading to hypokalemia and clinical cautions.
关键词
低血钾/躯体/奎硫平/利培酮/抗精神病药/精神分裂症Key words
Hypokalemia/somatic/quetiapine/risperidone/antipsychotic drugs/schizophrenia引用本文复制引用
基金项目
present study was funded by the Chinese National Science Foundation(81201057)
Shanghai Clinical Center for Psychiatric Disease()
Shanghai Municipal Commission Award(20124109)
Medical Guidance foundation of the Shanghai Science and Technology Committee(15411964400)
International Cooperation Foundation of the Shanghai Mental Health Center(2015-YJGJ-02)
出版年
2018
NETL
NSTL
万方数据