PURPOSE:To investigate the effects of chronic periodontitis on the quality of life and severity of the disease in patients with bronchiectasis.METHODS:A total of 80 bronchiectasis patients admitted to The Fourth Hospital of Changsha between April 2021 and April 2023 were randomly selected.Patients were divided into two groups according to whether they had moderate to severe chronic periodontitis:bronchiectasis with periodontitis group(n=45)and bronchiectasis without periodontitis group(n=35).The Qualify of Life Questionnaire for Bronchiectasi(QoL-B)was used to assess patients'quality.The severity of the disease was assessed using the Bronchiectasis Severity Index(BSI),and serum levels of hypersensitive C-reactive protein(hsCRP),tumor necrosis factor alpha(TNF-alpha),and interleukin-6(IL-6)were detected.SPSS 20.0 software package was used for data analysis.RESULTS:The QoL-B score of bronchiectasis with periodontitis group was significantly lower than that of bronchiectasis without periodontitis group,and the BSI score was significantly higher than that of bronchiectasis without periodontitis group(P＜0.05).The levels of hs-CRP,TNF-alpha and IL-6 in bronchiectasis with periodontitis were significantly higher than those in bronchiectasis without periodontitis group(P＜0.05).CONCLUSIONS:Chronic periodontitis shows significant adverse effects on both quality of life and disease severity in patients with bronchiectasis,which may be related to the common mechanism of inflammatory response between the two kinds of diseases.
Chronic periodontitisBronchiectasisQualify of lifehs-CRPTNF-αIL-6
NETL
NSTL
万方数据
