PURPOSE:To summarize the ultrasound,CT and MRI manifestations of Warthin-like mucoepidermoid carci-noma(WT-MEC),and to explore its imaging characteristics,so as to provide reference for clinical and preoperative diag-nosis.METHODS:The clinical information and imaging data of ultrasound,CT and MRI of 12 patients with WT-MEC diagnosed by pathology in Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine from Jan-uary 2017 to December 2021 were collected,and their specific characteristics were retrospectively summarized.RESULTS:Among the 12 WT-MEC patients,there were 7 males and 5 females,with an average age of(42.7±16)years.Seven cases underwent ultrasound examination,6 cases underwent CT examination,and 2 cases underwent MRI examination.Radio-logically,all the lesions presented as a solitary mass.11/12 lesions(91.7%)were identified as well-defined margins,and 10/12(83.3%)as solid-cystic masses.All solid-cystic lesions contained multiple cystic areas with variable sizes.On US images,most lesions showed mixed-echoic echogenicity(5/7,71.4%),poor vascularization(6/7,85.7%)and acoustic en-hancement(6/7,85.7%).CT revealed all the lesions(6/6,100%)as a soft-tissue mass with heterogeneous enhancement(5/6,83.3%).MRI imaging demonstrated the neoplasm with low or iso-signal intensity on plain T1WI and hyperintensity on T2WI.The heterogeneous enhancement was shown on contrast-enhanced T1WI.CONCLUSIONS:Most WT-MECs rep-resent as a solitary,well-defined,solid-cystic mass in the parotid gland.The neoplasm may be characterized by the multi-ple and variable-sized cystic components within the tumor.