Principlism in applied ethics demonstrates a path to apply ethics to specific practice.Unlike the deductive theory that relies on a moral system based on a certain highest principle and universal applicability,and the casuistry that relies on ana-logical evaluation based on perceptual judgment,principle ethicists seek the so-called median principle between abstract moral theory and concrete moral practice,as a normative guiding framework that provides value benchmarks and argumentative basis for people to deal with ethical conflicts.If non-harm,benefit,fairness,and autonomy are relatively classic ethical principles,then human rights,dignity,privacy,and responsibility are newly emerging and widely recognized ethical principles.The principle of the median in applied ethics has a self-evident character,and its fundamental basis is human moral intuition.These principles are in a coordinated and coherent relationship,and their content needs to be concretely explained and flexibly weighted according to the context in practice.