同济大学学报(医学版)2024,Vol.45Issue(1) :137-144.DOI:10.12289/j.issn.1008-0392.23100

全身麻醉药在精神类疾病治疗中的应用进展

Advances on the application of general anesthetics in treatment of mental disorders

黄雪迎 张兵 刘志强
同济大学学报(医学版)2024,Vol.45Issue(1) :137-144.DOI:10.12289/j.issn.1008-0392.23100

全身麻醉药在精神类疾病治疗中的应用进展

Advances on the application of general anesthetics in treatment of mental disorders

黄雪迎 1张兵 1刘志强1
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作者信息

  • 1. 同济大学附属妇产科医院麻醉科,上海 200040
  • 折叠

摘要

经典全身麻醉药氯胺酮于2019年获FDA批准用于耐药性抑郁症的临床治疗,该案例使全身麻醉药在精神类疾病治疗中的潜在价值成为了神经精神类疾病研究领域的热点.本文将围绕氯胺酮、N2O、七氟烷等全身麻醉药抗抑郁的作用及机制研究进展,以及全身麻醉药治疗产后抑郁症、焦虑症、孤独症、精神分裂症等精神类疾病研究进展进行综述.

Abstract

Ketamine is a classic general anesthetic.It has been approved by FDA for the clinical treatment of drug-resistant depression since 2019.This case indicates the potential value of general anesthetics in the treatment of mental disorders,thereafter it become a hot topic in the field of neuropsychiatric research.This article reviews the recent progress on the antidepressant effect and mechanism of general anesthetics such as ketamine,N2O and sevoflurane;as well as postpartum depression,anxiety,autism and schizophrenia.

关键词

全身麻醉药/氯胺酮/精神类疾病/抑郁症/产后抑郁症

Key words

general anesthetics/ketamine/mental fisorders/depression disorder/postpartum depression

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基金项目

国家自然科学基金面上项目(82371533)

出版年

2024
同济大学学报(医学版)
同济大学

同济大学学报(医学版)

CSTPCD
影响因子:0.51
ISSN:1008-0392
参考文献量66
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